Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 1;11:6. doi: 10.1186/s12920-018-0320-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Profiles of mutations detected in our study. a Exonic deletions and duplications detected by relative-depth comparisons. a-1 Heterozygous deletion involving exons 2−3 in the BRAT1 gene of patient 16 (P16), (a-2) heterozygous duplication involving exons 6−8 in the WWOX gene in patient 17 (P17). b Examples of chromosomal copy number alterations detected by off-target analysis of targeted next-generation sequencing results. b-1 Heterozygous deletion of the 15q11.2 region (downward arrow) observed in patient 27. b-2 Heterozygous duplication of the 19p13.3 region (upward arrow) observed in patient 28