Skip to main content
. Author manuscript; available in PMC: 2018 May 2.
Published in final edited form as: Circulation. 2017 Feb 16;135(18):1681–1689. doi: 10.1161/CIRCULATIONAHA.116.025140

Table 2.

Unadjusted and Adjusted Cox Regression Results For the Association Between Depression Recognition Groups and 1-Year Mortality.

Model 1 – Unadjusted, except for site HR 95% CI P-Value

Treated Depression(15 out of 223 deceased) 1.17 0.69-2.00 0.55
Untreated Depression(193 out of 3159 deceased) 1.83 1.35-2.48 <.0001
No Depression(reference; 55 out of 508 deceased)

Model 2 – Adjusted for demographics, socio-economic variables, disease severity, and clinical variables* HR 95% CI P-Value

Treated Depression 1.12 0.63-1.99 0.71
Untreated Depression 1.91 1.39-2.62 <.0001
No Depression (reference)

Three groups are compared: patients with (1) PHQ-9 scores <10 (no depression; reference); (2) PHQ-9 scores ≥10 and treated (treated depression); and (3) PHQ-9 scores ≥10 and not treated (untreated depression). Hazard Ratios (HR), corresponding 95% Confidence Intervals (CI), and P-values are presented.

*

Covariables in the model included: age, sex, race, marital status, education, insurance status, history of dyslipidemia, hypertension, peripheral vascular disease, diabetes, myocardial infarction, angina, coronary artery bypass graft, cerebrovascular accident, chronic kidney disease, chronic lung disease, chronic heart failure, cancer, current smoking, body mass index, family history of coronary artery disease, history of depression requiring treatment, Left ventricular systolic function <40%, Killip Class upon arrival, systolic blood pressure upon arrival, ST-Elevation myocardial infarction.