Table 2.
Model 1 – Unadjusted, except for site | HR | 95% CI | P-Value |
---|---|---|---|
| |||
Treated Depression(15 out of 223 deceased) | 1.17 | 0.69-2.00 | 0.55 |
Untreated Depression(193 out of 3159 deceased) | 1.83 | 1.35-2.48 | <.0001 |
No Depression(reference; 55 out of 508 deceased) | |||
| |||
Model 2 – Adjusted for demographics, socio-economic variables, disease severity, and clinical variables* | HR | 95% CI | P-Value |
| |||
Treated Depression | 1.12 | 0.63-1.99 | 0.71 |
Untreated Depression | 1.91 | 1.39-2.62 | <.0001 |
No Depression (reference) |
Three groups are compared: patients with (1) PHQ-9 scores <10 (no depression; reference); (2) PHQ-9 scores ≥10 and treated (treated depression); and (3) PHQ-9 scores ≥10 and not treated (untreated depression). Hazard Ratios (HR), corresponding 95% Confidence Intervals (CI), and P-values are presented.
Covariables in the model included: age, sex, race, marital status, education, insurance status, history of dyslipidemia, hypertension, peripheral vascular disease, diabetes, myocardial infarction, angina, coronary artery bypass graft, cerebrovascular accident, chronic kidney disease, chronic lung disease, chronic heart failure, cancer, current smoking, body mass index, family history of coronary artery disease, history of depression requiring treatment, Left ventricular systolic function <40%, Killip Class upon arrival, systolic blood pressure upon arrival, ST-Elevation myocardial infarction.