Table 4.
Characteristic (n = 17 464) | Adjusteda OR (95% CI) | P Value |
---|---|---|
1945–1965 birth cohort | ||
No | 1.0 | … |
Yes | 4.4 (3.8–5.1) | <.0001 |
Sexb | ||
Female | 1.0 | … |
Male | 1.4 (1.2–1.6) | <.0001 |
Race/ethnicityb | ||
White | 1.0 | … |
Black | 1.9 (1.6–2.2) | <.0001 |
Hispanic | 1.5 (1.2–2.0) | .0022 |
Asian | 0.6 (.4–1.1) | .0874 |
Other | 1.1 (.8–1.5) | .4142 |
Marital statusb | ||
Married | 1.0 | … |
Widowed/divorced | 1.5 (1.2–2.0) | .0019 |
Never married | 1.4 (1.2–1.6) | .0003 |
Elevated ALT | ||
No/unknown | 1.0 | … |
Yes | 4.8 (4.2–5.6) | <.0001 |
Injection drug use | ||
No/unknown | 1.0 | … |
Yes | 6.3 (5.2–7.6) | <.0001 |
Hemophilia | ||
No/unknown | 1.0 | … |
Yes | 1.1 (.7–1.7) | .6207 |
HIV infected | ||
No/unknown | 1.0 | … |
Yes | 1.0 (.8–1.3) | .7571 |
Abbreviations: ALT, alanine aminotransferase; CI, confidence interval; HIV, human immunodeficiency virus; OR, odds ratio.
Multilevel model adjusted for random effect of site and the following individual-level fixed effects: birth year, sex, race, marital status, injection drug use, elevated ALT, hemophilia, HIV status, and total number of encounters with healthcare system.
Missing values for sex, race/ethnicity, and marital status were multiply imputed.