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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Brain Res Bull. 2017 Aug 2;138:12–19. doi: 10.1016/j.brainresbull.2017.07.017

Figure 3. Female 118AA and 118GG and Male 118GG mice develop a conditioned place preference (CPP) to the rewarding effects of 2 g/kg of ethanol.

Figure 3

The rewarding effects of 2 g/kg of ethanol were assessed in male and female mice using CPP. The amount of time (seconds) mice spent on the ethanol-paired side both prior to (pre; open bars) and after (post; black bars) ethanol conditioning is shown. Female 118AA (AA; N=8) and 118GG (GG; N=8) and male 118GG (N=8) mice spent more time (in seconds) in the ethanol vs. saline-paired conditioning chamber. In contrast, male 118AA (N=8) mice failed to develop an ethanol CPP. Error bars represent the standard error of the mean (SEM). * = p < 0.001 between pre and post conditioning sessions.