Table 1.

Ethanol preference (%) and water intake (ml/kg) at each ethanol concentration was assessed using the unlimited access two-bottle choice assay.

EtOH Preference	6%	9%	12%	15%	18%
(%)
Female AA	61.16±2.46	62.11±0.76	65.24±1.45	63.37±1.11	61.95±1.29
Female GG	67.37±3.26	76.84±1.71*	80.56±1.67*	76.44±1.53	64.83±1.17
Male AA	66.66±3.49	70.13±2.50	65.31±1.69	62.26±2.57	53.60±1.71
Male GG	82.34±1.53	82.15±2.02	80.15±2.52	72.59±2.12	58.73±2.38
Water Intake	6%	9%	12%	15%	18%
(ml/kg)
Female AA	60.07±3.90	65.23±2.55	56.09±1.90	61.12±2.35	70.71±5.03
Female GG	55.23±5.76	43.53±2.82	37.23±3.81	46.91±4.40	76.25±6.42
Male AA	39.53±4.87	34.11±2.59	38.72±1.53	41.37±2.49	52.84±2.89
Male GG	23.86±2.53	21.83±1.58	26.00±2.34	33.46±3.19	53.68±3.49

Two-way mixed ANOVAs were performed to analyze genotype differences in ethanol preference and water intake. There were no differences among male 118AA (AA; N=10) or 118GG (GG; N=5) mice in either water intake or ethanol preference. However, female 118GG (N=19) mice did show higher ethanol preference at 9% and 12% ethanol compared to their 118AA (N=21) counterparts. Error bars represent the standard error of the mean (SEM).

^*= p<0.05 compared to female AA mice.