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. 2018 Jan 29;9:75. doi: 10.3389/fimmu.2018.00075

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Copyright © 2018 Patra and Choi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Stability parameters of toll/interleukin 1 receptor domain-containing adaptor protein (TIRAP) as a function of simulation time. (A–C) Root mean square deviation; (D–F) root mean square fluctuation; and (G–I) radius of gyration. The left and center columns contain stability parameters for phosphatidylinositol 4,5-bisphosphate (PIP2)-bound and unbound TIRAPs, respectively, while the right column contains stability parameters for a mutant TIRAP (K15 → A, K16 → A, K31 → A, and K32 → A). Also, note that each plot shows parameters for chain (A) (black) and chain (B) (red).