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. 2017 Dec 15;9(4):4461–4474. doi: 10.18632/oncotarget.23286

Figure 2. Histopathological evaluation of OA in a rat OA model treated with different inhibitors of PLCγ1 and Akt for 2 month.

Figure 2

(A) Representatives images of Safranin O –Fast green staining from the rats treated by different inhibitors of PLCγ1 and Akt after ACLT+MMx (original magnification ×100). (B) Graph indicating the relative cartilage thickness of each femur condyle (from superficial zone to tidemark). (C) Graph indicating the OARSI scores (*P < 0.05, **P < 0.01, ****P < 0.0001, vs NS group).