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. 2017 Dec 17;9(4):4496–4510. doi: 10.18632/oncotarget.23388

Figure 8. Effect of CAL62 and OCUT cells on IMR90 fibroblasts.

Figure 8

(A) Q-RT-PCR of Shh in IMR90 upon stimulation with conditioned medium derived from CAL62 and OCUT cells. (B) Q-RT-PCR measuring the expression of Gli1 in IMR90 stimulated with cancer cells (CAL62/OCUT) conditioned medium. Shh ligand stimulation was used as positive control. **p = ≤ 0.01; *p = ≤ 0.05. (C) Schematic representation of Shh pathway activation mechanisms in thyroid cancer cells.