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(A) Classification of VHL genotype based on VHL point mutations and copy number alterations (CNA). (B–H) mRNA expression levels of indicated genes determined by RNA-sequencing of 418 tumor samples in TCGA Provisional Kidney Renal Clear Cell Carcinoma dataset, grouped on the basis of VHL point mutations, VHL copy number alterations, or putative VHL genotype. Columns, mean; bars, SEM.
