Table 4. Univariate and multivariate analysis of training set and validation.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Pa value | Hazard ratio(95% CI) | P valuea | Hazard ratio (95% CI) | |
| Training set | ||||
| 7th AJCC stage (ref: I) | <0.001 | 2.598 (2.256, 2.991) | <0.001 | |
| II | 0.003 | 3.810 (1.573, 9.232) | ||
| III | <0.001 | 12.926 (5.699, 29.318) | ||
| IV | <0.001 | 24.239 (10.624, 55.301) | ||
| Differentiated type | 0.009 | 1.376 (1.084, 1.748) | 0.042 | 1.284 (1.009, 1.635) |
| Risk score | <0.001 | 2.082 (1.673, 2.592) | 0.015 | 1.323 (1.056, 1.658) |
| Validation set | ||||
| 7th AJCC stage (ref: I) | <0.001 | 2.598 (2.256, 2.991) | <0.001 | |
| II | 0.003 | 3.466 (1.527, 7.869) | ||
| III | <0.001 | 9.610 (4.472, 20.649) | ||
| IV | <0.001 | 19.974 (9.271, 43.0.32) | ||
| Location (ref: Lower) | <0.001 | 2.535 (2.203, 2.917) | 0.004 | |
| Upper | 0.027 | 1.369 (1.036, 1.809) | ||
| Middle | 0.470 | 0.895 (0.662, 1.209) | ||
| Age | 0.001 | 1.486 (1.181, 1.869) | 0.001 | 1.498 (1.185, 1.892) |
| Risk score | <0.001 | 2.417 (1.933, 3.023) | 0.001 | 1.446 (1.160, 1.852) |
AJCC, American Joint Committee on Cancer.
a Cox proportional hazards model.