Table 3. The interaction between gene and gene in the change of blood pressure.
| Gene-gene | Genotype | Systolic blood-pressure | Diastolic blood-pressure | |||
|---|---|---|---|---|---|---|
| OR(95%CI) | ORa(95%CI) | OR(95%CI) | ORa(95%CI) | |||
| rs3804610* rs9818496 | TT | CC | 1 | 1 | 1 | 1 |
| TT | CT/TT | 0.931(0.425∼2.038) | 0.902(0.461∼1.767) | 0.802(0.528∼1.391) | 0.782(0.498∼1.291) | |
| TC/CC | CC | 1.037(0.638∼1.687) | 1.005(0.603∼1.623) | 1.332(0.806∼2.200) | 1.257(0.697∼1.919) | |
| TC/CC | CT/TT | 1.558(1.078∼2.289) | 1.498(1.016∼2.260) | 1.465(1.006∼2.133) | 1.339(0.891∼2.112) | |
| ORint=1.272(1.043∼1.551), P=0.017 | ORint=1.152(0.085∼1.951), P=0.087 | |||||
| rs6784267* rs9818496 | CC | CC | 1 | 1 | 1 | 1 |
| CC | CT/TT | 1.157(0.717∼1.869) | 1.148(0.703∼1.824) | 0.856(0.618∼1.491) | 0.793(0.513∼1.301) | |
| CT/TT | CC | 1.518(0.941∼2.450) | 1.432(0.881∼2.327) | 1.057(0.683∼1.636) | 0.923(0.431∼1.977) | |
| CT/TT | CT/TT | 1.609(1.108∼2.345) | 1.552(1.041∼2.324) | 1.490(1.024∼2.168) | 1.366(0.914∼2.041) | |
| ORint=1.461(1.172∼1.822), P=0.001 | ORint=1.172(0.083∼1.976), P=0.093 | |||||
| rs6784267* rs3804610 | TT | CC | 1 | 1 | 1 | 1 |
| TT | CT/TT | 1.157(0.717∼1.869) | 1.148(0.703∼1.824) | 0.856(0.618∼1.491) | 0.793(0.513∼1.301) | |
| TC/CC | CC | 1.518(0.941∼2.450) | 1.432(0.881∼2.327) | 1.057(0.683∼1.636) | 0.923(0.431∼1.977) | |
| TC/CC | CT/TT | 1.609(1.108∼2.345) | 1.552(1.041∼2.324) | 1.490(1.024∼2.168) | 1.366(0.914∼2.041) | |
| ORint=1.461(1.172∼1.822), P=0.001 | ORint=1.172(0.083∼1.976), P=0.093 | |||||
ORa were adjusted for age, gender, BMI, smoking status, alcohol use status, and education level, BG, TG, TC, HDL, LDL, CRP.