Table 4. The interaction between gene and As exposure in the change of blood pressure.
| Gene site | Genotype | As | Systolic blood-pressure | Diastolic blood-pressure | ||
|---|---|---|---|---|---|---|
| OR(95%CI) | ORa(95%CI) | OR(95%CI) | ORa(95%CI) | |||
| rs9818496 | CC | 0-4 | 1 | 1 | 1 | 1 |
| CC | >4 | 1.567(1.312∼2.762) | 1.618(0.526∼2.817) | 1.301(0.572∼2.731) | 1.324(0.717∼2.946) | |
| CT/TT | 0-4 | 1.312(0.518∼4.723) | 1.354(0.753∼2.574) | 1.245(0.372∼3.381) | 1.271(0.417∼3.842) | |
| CT/TT | >4 | 2.437(1.318∼4.483) | 2.682(1.348∼5.547) | 1.547(0.922∼2.581) | 1.565(0.927∼2.876) | |
| ORint=1.496(1.149∼1.947), P=0.003 | ORint=1.308(0.874∼1.902), P=0.067 | |||||
| rs3804610 | TT | 0-4 | 1 | 1 | 1 | 1 |
| TT | >4 | 1.567(1.312∼2.762) | 1.618(0.526∼2.817) | 1.301(0.572∼2.731) | 1.324(0.717∼2.946) | |
| CT/CC | 0-4 | 1.312(0.518∼4.723) | 1.354(0.753∼2.574) | 1.245(0.372∼3.381) | 1.271(0.417∼3.842) | |
| CT/CC | >4 | 2.437(1.318∼4.483) | 2.682(1.348∼5.547) | 1.547(0.922∼2.581) | 1.565(0.927∼2.876) | |
| ORint=1.496(1.149∼1.947), P=0.003 | ORint=1.308(0.874∼1.902), P=0.067 | |||||
| rs6784267 | CC | 0-4 | 1 | 1 | 1 | 1 |
| CC | >4 | 1.453(1.002∼3.244) | 1.461(0.872∼2.414) | 1.352(0.836∼2.463) | 1.399(0.856∼2.589) | |
| CT/TT | 0-4 | 1.262(1.116∼2.784) | 1.286(0.714∼2.234) | 1.286(0.736∼2.363) | 1.327(0.906∼2.398) | |
| CT/TT | >4 | 1.789(1.132∼2.976) | 1.824(1.094∼2.435) | 1.493(0.950∼2.463) | 1.539(0.956∼2.979) | |
| ORint=1.312(1.081∼1.593), P=0.006 | ORint=1.277(1.055∼1.546), P=0.052 | |||||
ORa were adjusted for age, gender, BMI, smoking status, alcohol use status, and education level, BG, TG, TC, HDL, LDL, CRP.