Figure 3. In vitro cytotoxicity assay of promiximab and promiximab-DUBA.

Small cell lung cancer cell lines and human NK cells were treated with various concentrations of promiximab and promiximab-DUBA for 72 h. Untreated cells were used as controls. The IC50 values obtained after a 72 h cell exposure were summarized in Table. Cell viability was determined by three independent experiments of CCK-8 assay and calculated as the absorbance ratio of treated to control groups. Data were presented as Mean±SEM.