Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 2;8:2202. doi: 10.1038/s41598-018-20727-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Expression profiles of CC-lncRNAs according to the donors’ age. (A) Histograms show the expression level of six lncRNAs (IL10RB-AS1, APOA1-AS, IGF2BP2-AS1, LINC00548, PSMB8-AS1 and LAMTOR5-AS1) in CC samples from young (<35 years) and older patients (>40 years of age) (n = 9 sample/group). The number of reads is shown on the y-axis as arbitrary units determined by the RNA-seq analysis. *Significant difference with FDR ≤0.05 according to SAM. (B) Validation by qRT-PCR analysis of the expression profile of some lncRNAs that are differentially expressed in older and younger patients (n = 5 samples/group). The signal intensity (arbitrary units) for each lncRNA is shown on the Y-axis; **Significant difference with p-value = 0.0079. NS: not significant.