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. 2018 Feb 2;8:2280. doi: 10.1038/s41598-018-20772-9

Table 1.

Chemical structures of 221 analogs.

Compound R1 R2 R3
Synthetic compounds group 1Inline graphic S1a graphic file with name 41598_2018_20772_Figb_HTML.gif -H -H
S1b graphic file with name 41598_2018_20772_Figc_HTML.gif -H -CH3
S1c graphic file with name 41598_2018_20772_Figd_HTML.gif -CH3 -H
S1d graphic file with name 41598_2018_20772_Fige_HTML.gif -F -H
Synthetic compounds group 2 Inline graphic Compound R1 R2 R3
221 -CH3 graphic file with name 41598_2018_20772_Figg_HTML.gif -H
S2a -CH2CH2OH graphic file with name 41598_2018_20772_Figh_HTML.gif -H
S2b -H graphic file with name 41598_2018_20772_Figi_HTML.gif -H
S2c -CH3 graphic file with name 41598_2018_20772_Figj_HTML.gif -H
S2d -CH3 graphic file with name 41598_2018_20772_Figk_HTML.gif -CH3
S2e graphic file with name 41598_2018_20772_Figl_HTML.gif graphic file with name 41598_2018_20772_Figm_HTML.gif -H
S2f -CH3 graphic file with name 41598_2018_20772_Fign_HTML.gif -H
Commercially available analogs group 1 Inline graphic Compound R1 R2 R3 R4 R5
390 graphic file with name 41598_2018_20772_Figp_HTML.gif -H -H -H -CH3
391 graphic file with name 41598_2018_20772_Figq_HTML.gif -H -OCH3 -OH graphic file with name 41598_2018_20772_Figr_HTML.gif
394 -CH2CH3 -H -H -H graphic file with name 41598_2018_20772_Figs_HTML.gif
395 graphic file with name 41598_2018_20772_Figt_HTML.gif -CH3 -H -H graphic file with name 41598_2018_20772_Figu_HTML.gif
396 -CH2CH3 -H -F -H graphic file with name 41598_2018_20772_Figv_HTML.gif
397 graphic file with name 41598_2018_20772_Figw_HTML.gif -H -CH3 -H -CH3
Commercially available analogs group 2 Inline graphic Compound R1 R2 R3 R4
221 -CH3 =O graphic file with name 41598_2018_20772_Figy_HTML.gif -OH
312 -H =O graphic file with name 41598_2018_20772_Figz_HTML.gif -OH
385 -CH3 =O graphic file with name 41598_2018_20772_Figaa_HTML.gif -OH
387 -H =O graphic file with name 41598_2018_20772_Figab_HTML.gif -OH
Uncategorized commercially available analogs Compound Chemical illucture
310 graphic file with name 41598_2018_20772_Figac_HTML.gif
384 graphic file with name 41598_2018_20772_Figad_HTML.gif
389 graphic file with name 41598_2018_20772_Figae_HTML.gif
392 graphic file with name 41598_2018_20772_Figaf_HTML.gif