Table 5.
Replication of H9N2 influenza viruses in micea.
| O/BJ/293/13 | O/YN/438/14 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| lung | heart | brain | spleen | liver | Lung | heart | brain | spleen | liver | |
| 3 dpi | 3.2 ± 0.6 (3/3)b | — | — | — | — | 2.1(1/3) | — | — | — | — |
| 5 dpi | 2.3(1/3) | — | — | — | — | — | — | — | — | — |
aSix-week-old female BALB/c mice were inoculated intranasally with 106 EID50 of H9N2 influenza viruses. Three mice from each group were killed on 3 dpi and 5 dpi and virus titers in samples of heart, liver, spleen, lung and brain were determined. bThe average virus titer was expressed as log10EID50/ml ± SD(positive number/total number), with the limit of virus detection at 1.2 log10 EID50/ml. c— indicates that virus was not recovered from the sample.