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. 2017 Dec 26;16(1):95–115. doi: 10.1007/s12021-017-9352-y

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Scatter modelling and validation setup. a: Voxel-driven scatter model (VSM) based on single scatter simulation. It assumes that photons emitted at E (shown in the sagittal plane) along $\hat{u}$ are unscattered and detected while the opposing photons emitted along $\hat{a}$ are assumed scattered from the original trajectory and then detected on the detector ring. b: Validation Monte Carlo setup using SimSET with ¹⁸F-florbetapir and the Siemens Biograph mMR geometry. Top row includes the transaxial and sagittal μ-map images whereas the bottom row consists of the corresponding emission images for brain and point source (marked point E) simulations