Table 14.
MKL modelling of the comparison of ‘demented’ vs ‘healthy’, based on the Brodmann atlas
| Region | Area Description | Contribution (%) | Size | ER |
|---|---|---|---|---|
| brodmann area 7 | Superior Parietal lobule and part of precuneus | 11.56 | 6488.00 | 63.10 |
| brodmann area 46 | Dorsolateral prefrontal cortex | 9.16 | 740.00 | 62.50 |
| brodmann area 6 | Premotor cortex and Supplementary motor Cortex | 8.80 | 8215.00 | 61.90 |
| brodmann area 22 | Superior temporal gyrus | 7.26 | 2439.00 | 58.00 |
| brodmann area 44 | Pars opercularis of the inferior frontal gyrus | 6.51 | 885.00 | 59.30 |
| brodmann area 45 | Pars triangularis of the inferior frontal gyrus | 5.58 | 546.00 | 56.50 |
| brodmann area 18 | Secondary visual cortex (V2) | 4.36 | 4810.00 | 49.30 |
| brodmann area 24 | Ventral anterior cingulate cortex | 4.07 | 2345.00 | 54.40 |
| brodmann area 20 | Inferior temporal gyrus | 3.89 | 4218.00 | 50.80 |
| brodmann area 17 | Primary visual cortex (V1) | 3.47 | 1101.00 | 53.70 |
| Caudate Tail | 3.36 | 8.00 | 54.40 | |
| brodmann area 19 | Associative visual cortex (V3,V4,V5) | 2.94 | 4725.00 | 43.90 |
| brodmann area 38 | Temporopolar area | 2.73 | 2471.00 | 42.70 |
| brodmann area 34 | Dorsal entorhinal cortex | 2.40 | 608.00 | 36.90 |
| brodmann area 39 | Angular gyrus | 1.87 | 1783.00 | 39.10 |
| brodmann area 3 | Part of primary somatosensory cortex | 1.76 | 1064.00 | 26.70 |
| brodmann area 2 | Part of primary somatosensory cortex | 1.68 | 812.00 | 39.20 |
| brodmann area 10 | Anterior prefrontal cortex | 1.54 | 4066.00 | 30.30 |
| brodmann area 42 | Auditory cortex | 1.48 | 433.00 | 38.90 |
| brodmann area 23 | Ventral posterior cingulate cortex | 1.47 | 866.00 | 26.00 |
| brodmann area 36 | Ectorhinal area | 1.39 | 1032.00 | 33.40 |
| Caudate Body | 1.28 | 521.00 | 37.70 | |
| Hippocampus | 1.28 | 572.00 | 21.00 | |
| brodmann area 47 | Pars orbitalis, part of the inferior frontal gyrus | 1.18 | 2550.00 | 20.80 |
| Red Nucleus | 1.17 | 7.00 | 36.70 | |
| brodmann area 1 | Part of primary somatosensory cortex | 1.01 | 57.00 | 31.90 |
| Putamen | 0.92 | 2452.00 | 28.90 | |
| Mammillary Body | 0.90 | 60.00 | 31.60 | |
| Lateral Posterior Nucleus | 0.59 | 45.00 | 26.60 | |
| brodmann area 8 | Part of the frontal cortex, it includes the frontal eye fields | 0.57 | 2473.00 | 14.50 |
| Ventral Lateral Nucleus | 0.51 | 74.00 | 25.50 | |
| brodmann area 5 | Somatosensory Association Cortex | 0.49 | 1044.00 | 18.70 |
| brodmann area 31 | Dorsal Posterior cingulate cortex | 0.48 | 3310.00 | 13.60 |
| brodmann area 40 | Supramarginal gyrus | 0.39 | 4753.00 | 9.50 |
| Lateral Globus Pallidus | 0.28 | 53.00 | 12.70 | |
| brodmann area 9 | Dorsolateral prefrontal cortex | 0.27 | 3740.00 | 12.80 |
| brodmann area 29 | Retrosplenial cingulate cortex | 0.27 | 203.00 | 13.10 |
| Medial Dorsal Nucleus | 0.26 | 573.00 | 13.10 | |
| Medial Geniculum Body | 0.22 | 5.00 | 20.80 | |
| brodmann area 11 | Part of the orbitofrontal cortex | 0.20 | 4067.00 | 5.40 |
| brodmann area 13 | Insular Cortex | 0.18 | 3527.00 | 8.20 |
| brodmann area 33 | Part of anterior cingulate cortex | 0.16 | 26.00 | 20.00 |
| Corpus Callosum | 0.08 | 109.00 | 4.10 | |
| Caudate Head | 0.03 | 740.00 | 4.40 | |
| Ventral Posterior Medial Nucleus | 0.00 | 49.00 | 3.70 | |
| brodmann area 28 | Ventral entorhinal cortex | 0.00 | 609.00 | 3.80 |
Regions ranked further (i.e. rank >46) have a perfectly null contribution to the model. ER stands for Expected Ranking. The region size is displayed in voxels. The weights were averaged across folds (except for computing ER)