Table 1.
Patient characteristics and colonization status
| All patients | Noncolonized | Colonized | |
|---|---|---|---|
| Basic demographic characteristics | |||
| Group size, no. (%) | 120 (100) | 69 (57.5) | 51 (42.5) |
| Sex distribution: female/male, no. (%) | 50 (42)/70 (58) | 29 (42)/40 (58) | 21(41)/30 (59) |
| Age at HCT, median (range), years | 41 (19–67) | 38 (19–67) | 44 (21–66) |
| Age > 40 years, no. (%) | 59 (49) | 39 (56.5) | 20 (39) |
| Diagnosis | |||
| AML/MDS, no. (%) | 65 (54) | 39 (57) | 26 (51) |
| ALL, no. (%) | 25 (21) | 13 (19) | 12 (23) |
| CML/MF/CMML, no. (%) | 14 (11.5) | 9 (13) | 5 (10) |
| NHL/HL/CLL/MM, no. (%) | 10 (8.5) | 6 (9) | 4 (8) |
| sAA/PNH, no. (%) | 6 (5) | 2 (3) | 4 (8) |
| Transplant characteristics | |||
| Donor type: MUD or MMUD/MSD, no. (%) | 68 (57)/52(43) | 40 (58)/29 (42) | 28 (55)/23 (45) |
| Graft source: PB/BM, no. (%) | 111 (92.5)/9 (7.5) | 64 (93)/5 (7) | 47 (92)/4 (8) |
| Conditioning regimen: MAC/RTC or RIC, no. (%) | 92 (77)/24 (20) | 55 (80)/12 (17) | 37 (72.5)/12 (23.5) |
| Conditioning regimen: immunoablation, no. (%) | 4 (3) | 2 (3) | 2 (4) |
| Day of neutrophil engraftment, median (range) | 23 (14-not achieved) | 23 (14-not achieved) | 23 (14-not achieved) |
| ANC > 500/mm3 before day 20, no. (%) | 36 (30) | 24 (35) | 12 (24) |
HCT hematopoietic cell transplantation, AML/MDS acute myeloid leukemia/myelodysplastic syndrome, ALL acute lymphoblastic leukemia, CML chronic myeloid leukemia, MF myelofibrosis, CMML chronic myelomonocytic leukemia, NHL non-Hodgkin lymphoma, HL Hodgkin lymphoma, CLL chronic lymphocytic leukemia, MM multiple myeloma, sAA severe aplastic anemia, PNH paroxysmal nocturnal hemoglobinuria, MUD matched unrelated donor, MMUD mismatched unrelated donor, MSD matched sibling donor, MAC myeloablative conditioning, RTC reduced toxicity conditioning, RIC reduced intensity conditioning, ANC absolute neutrophil count