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. 2018 Feb 2;8:2307. doi: 10.1038/s41598-018-20649-x

Table 3.

Significant variations in soluble immune factors.

Healthy Intermediate Vaginosis Healthy vs Intermediate Healthy vs Vaginosis Intermediate vs Vaginosis
cytokines
IL1α 62 ± 16 35 ± 6 295 ± 118 0.999 0.08 0.03
IL1β 43 ± 28 16 ± 7.5 215 ± 126 0.999 0.064 0.017
IL1ra 1.3E5 ± 2.5E4 3E5 ± 4.6E4 1.5E9 ± 1E9 0.014 0.000 0.605
IL2 1.4 ± 0.44 4.3 ± 0.6 4 ± 0.9 0.000 0.020 0.999
IL3 121 ± 9 87 ± 10 97 ± 10 0.028 0.277 0.999
IL17 12 ± 1.9 5 ± 0.5 7 ± 1 0.013 0.209 0.999
IL18 108 ± 21 216 ± 135 1373 ± 593 0.999 0.000 0.001
MIF 219 ± 113 780 ± 606 2353 ± 890 0.999 0.019 0.237
LIF 22 ± 1.3 12 ± 1.5 23 ± 2.7 0.000 0.999 0.002
SCF 23 ± 3.3 12 ± 2.8 18 ± 2.9 0.021 0.999 0.207
TNFα 14 ± 1.7 14 ± 2.3 31 ± 6 0.999 0.002 0.025
TNFβ 14 ± 1.8 9 ± 0.3 10 ± 0.6 0.013 0.999 0.271
chemokynes
IL8 157 ± 26 127 ± 45 351 ± 95 0.646 0.430 0.047
MCP1 9 ± 1.6 4.6 ± 0.5 5 ± 0.5 0.003 0.061 0.999
MIG 309 ± 119 188 ± 122 488 ± 178 0.08 0.999 0.016
MIP1α 1.7 ± 0.3 1.4 ± 0.4 2 ± 0.4 0.561 0.180 0.012
RANTES 11 ± 3.7 17 ± 12 24 ± 6 0.406 0.137 0.005
growth factors
FGFβ 32 ± 3 17 ± 1.2 18 ± 1.6 0.008 0.019 0.999
GMCSF 109 ± 4.5 81 ± 6.4 75 ± 4.6 0.015 0.000 0.593

Data are shown as the mean value (pg/mL) ± standard error of mean. Comparisons between groups were performed using a non-parametric Kruskal-Wallis test. The p values are adjusted for multiple comparisons. Significant p values are highlighted in bold.