Table 3.

Stratified association analysis of per 1-S.D. decrease of ln-transformed telomere length in stroke subtypes.

Variables	Atherothrombotic stroke				Lacunar stroke
	Cases/control	OR (95% CI)	P*	P interaction †	Cases/control	OR (95% CI)	P*	P interaction †
Gender
Male	121/284	1.46 (1.13–1.89)	0.004	0.06	130/284	0.68 (0.52–0.89)	0.005	0.40
Female	103/332	1.43 (1.11–1.85)	0.005		95/332	0.70 (0.52–0.94)	0.019
Age
≤50	23/99	1.66 (0.88–3.13)	0.12		20/99	0.79 (0.37–1.70)	0.55	0.09
51–60	57/134	1.59 (1.15–2.19)	0.005	0.07	42/134	0.75 (0.50–1.12)	0.16
≥60	144/383	1.38 (1.10–1.73)	0.006		163/383	0.67 (0.53–0.85)	0.001
BMI
<25	144/464	1.44 (1.14–1.82)	0.002	0.25	163/464	0.58 (0.45–0.75)	<0.001	0.09
≥25	80/152	1.66 (1.25–2.20)	<0.001		62/152	1.12 (0.80–1.58)	0.51
Smoking
No	172/580	1.48 (1.22–1.80)	<0.001	0.81	162/580	0.69 (0.55–0.86)	0.001	0.92
Yes	52/36	1.40 (0.91–2.14)	0.12		63/36	0.72 (0.45–1.13)	0.15
Alcohol intake
No	176/569	1.41 (1.17–1.71)	<0.001	0.79	181/569	0.70 (0.56–0.86)	0.001	0.82
Yes	48/47	1.50 (0.93–2.41)	0.10		44/47	0.74 (0.47–1.16)	0.10
Hypertension
No	86/303	1.86 (1.42–2.45)	<0.001	0.001	107/303	0.59 (0.43–0.81)	0.001	0.055
Yes	138/313	1.35 (1.06–1.72)	0.016		118/313	0.83 (0.63–1.10)	0.19
Diabetes
No	166/514	1.40 (1.14–1.71)	0.001	0.55	189/514	0.67 (0.54–0.83)	0.001	0.37
Yes	58/102	1.83 (1.22–2.74)	0.004		36/102	0.97 (0.55–1.72)	0.91

^*OR (95% CI) and P values were obtained with multivariate logistic regression analysis after adjustment for conventional vascular risk factors, including age, gender, systolic and diastolic BP, fasting glucose, total cholesterol, triglycerides, plasma uric acid, body mass index, smoking status, alcohol intake, history of hypertension, diabetes and previous CHD, except for the stratification variable. ^†P_interaction was obtained by evaluating interaction terms.