Table 4.
Associations between leucocyte telomere length and stroke in the second case/control study of Southern Chinese population.
| Variables* | Highest tertile | Middle tertile | Lowest tertile | P trend | Per 1-S.D. decrease in Ln-transformed telomere length | P |
|---|---|---|---|---|---|---|
| Controls (n = 875) | 292 | 292 | 291 | |||
| Total cases (n = 773) | 209 | 306 | 258 | |||
| ORs (95% CI) | 1.00 | 1.15 (0.86–1.54) | 0.85 (0.63–1.15) | 0.27 | 0.92 (0.83–1.03) | 0.13 |
| Atherothrombotic stroke (n = 329) | 78 | 130 | 121 | |||
| ORs (95% CI) | 1.00 | 1.38 (0.93–2.04) | 1.52 (1.08–2.14) | 0.01 | 1.11 (1.00–1.23) | 0.05 |
| Lacunar infarction (n = 222) | 71 | 90 | 61 | |||
| ORs (95% CI) | 1.00 | 1.10 (0.73–1.64) | 0.60 (0.39–0.93) | 0.02 | 0.79 (0.68–0.92) | 0.003 |
| Hemorrhagic stroke (n = 222) | 60 | 86 | 76 | |||
| ORs (95% CI) | 1.00 | 1.15 (0.72–1.84) | 0.84 (0.52–1.36) | 0.45 | 0.97 (0.83–1.14) | 0.72 |
*OR (95% CI) was obtained with multivariate logistic regression analysis after adjusting age, gender, BMI, and conventional vascular factors as mentioned in Table 2.