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. 2018 Jan 29;9:38. doi: 10.3389/fimmu.2018.00038

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Copyright © 2018 Chiurchiù, Leuti and Maccarrone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic pathways of the main families of endogenous bioactive lipids. 2-AG, 2 arachidonoylglycerol; AA, arachidonic acid; AEA, arachidonoylethanolamide; C1P, ceramide-1-phosphate; CK, ceramide kinase; COX, cyclooxygenase; DAGL, diacylglycerol lipase; DHA, docosahexaenoic acid; DPA, docosapentaenoic acid; EPA, eicosapentaenoic acid; FAAH, fatty acid amide hydrolase; HETEs, hydroxyeicosatetraenoic acids; LOX, lipoxygenase; LPA, lysophosphatidic acid; LPC, lysophosphatidilcholine; LPI, lysophosphatidylinositol; LPSer, lysophosphatidylserine; LTs, leukotrienes; LX, lipoxin; Lyso-PLD, lyso-phospholipase D; MAGL, monoacylglycerol lipase; MaR, maresin; NAPE-PLD, N-arachidonoylphosphatidylethanolamide-specific phospholipase D; Pal-CoASH, palmitoyl coenzyme A; PD, protectin; PDX, protectin DX; PGs, prostaglandins; PLA₂, phospholipase A₂; Rv, resolvin; S1P, sphingosine-1-phosphate; SK, sphingosine kinase; TXs, thromboxanes.