Table 1.
Clinical and virological characteristics of the patients
| HBsAg-positive HCC (n = 10) |
OBI-related HCC (n = 9) |
P value | |
|---|---|---|---|
| Age (years) | 53.6 ± 11.5 | 69.7 ± 5.6 | 0.002* |
| Sex (male/female) | 9/1 | 8/1 | 0.737 |
| PLT (× 104/mm3) | 17.9 ± 4.9 | 23.0 ± 8.4 | 0.131 |
| AST (U/L) | 59.1 ± 37.9 | 38.9 ± 15.0 | 0.145 |
| ALT (U/L) | 33.2 ± 11.0 | 31.4 ± 15.4 | 0.782 |
| HbA1c (%) | 5.29 ± 0.45 | 5.46 ± 0.50 | 0.461 |
| HBsAg (mIU/ml) | 3278 ± 3045 | 0 | |
| Anti-HBc antibody (C.O.I.) | 12.6 ± 1.8 | 10.1 ± 1.2 | 0.002* |
| HBV DNA (log copies/ml) | 5.41 ± 1.84 | < 2.06 | |
| Hyaluronic acid (ng/ml) | 62.7 ± 51.0 | 107.1 ± 123.2 | 0.338 |
| Fibrosis (F0–2/F3–4) | 4/6 | 4/5 | 0.605 |
| Total reads (mean ± SD) | 4,451,542 ± 2,357,824 | 3,708,797 ± 2,365,839 | 0.503 |
| Mapping reads (mean ± SD) | 1,075,698 ± 845,602 | 619,866 ± 347,934 | 0.144 |
| Coverage (mean ± SD) | 131,921 ± 97,014 | 77,279 ± 49,215 | 0.139 |
*P < 0.05