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. 2018 Feb 3;19:23. doi: 10.1186/s12931-018-0723-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of sex on airway function after infection and methacholine (50 mg/mL). Airway functions such as respiratory resistance (Rrs) panel a, compliance (Crs) panel b, elastance (Ers) panel c, and constant phase model parameters airway resistance (Rn), tissue damping (g), and tissue elastance (h), (panels d, e, f) were measured in SP-A1 (6A², 6A⁴), SP-A2 (1A⁰, 1A³), SP-A1/SP-A2 (6A2/1A⁰, co-ex), and SP-A (KO) male and female mice after challenge with methacholine (50 mg/mL). Data are expressed as mean ± SD (4 replicates per group). *p < 0.05