Table 2.

EPIC-NSW study flowchart

Follow-up schedule	Screening/enrolment/baseline	Follow-up 1	Subsequent Follow-ups
Timeline	Week −2 or 0a, b	Month 1	Month 3 and every 3 months thereafterc
Informed consent	X
Review eligibility	X	X	X
Medical historyd	X
Renal function (creatinine clearance)	X		Xe
Serious adverse events, pregnancy (if applicable)		X	X
Hepatitis C testing	X		Xf
STI testing g	X		X
HIV testingg	X	X	X
Dispense study medication	X	X	X
Survey of adherence and behaviour	X		Xh

^aResults of all tests conducted in the preceding 2 weeks are accepted at enrolment. Only the HIV test should be conducted not earlier than 7 days within starting PrEP

^bVisits may be combined if HIV test result available

^cAs per NSW and National PrEP guidelines

^dInformation in relation to eligibility for PrEP

^eAt 3 months and every 6 months thereafter

^fConsider annual testing for HCV, or more often in men with substantial risk

^gHIV and STI tests conducted per current standard of care according to the National HIV and STI testing guidelines. Data obtained electronically quarterly from ACCESS study

^hBehavioural data collected on consenting participants