Table 1.
Patient characteristics
| all pts. (n = 131) | DCIS pts. (n = 96) | miCa pts. (n = 35) | p value(*) | |
|---|---|---|---|---|
| mean age [range] | 56 [36–84] | 56 [36–84] | 54 [38–78] | NS |
| initial management | ||||
| lumpectomy | 89 (68%) | 68 (71%) | 21 (60%) | NS |
| mastectomy | 42 (32%) | 28 (29%) | 14 (40%) | |
| adjuvant treatment | ||||
| radiotherapy | 89 (68%) | 68 (71%) | 21 (60%) | NS |
| endocrine treatment | 10 (8%) | 1 (1.0%) | 9 (26%) | < 0.0001 |
| cytotoxic treatment | 2 (2%) | 0 (0.0%) | 2 (6%) | 0.03 |
| observation | 39 (30%) | 27 (28%) | 12 (34%) | NS |
| trastuzumab | 1 (1%) | 0 (0%) | 1 (3%) | NS |
| recurrences | 18 (14%) | 14 (14%) | 4 (11%) | NS |
| DFS at 5 years | 94% (n = 124) | 94% (n = 91) | 94% (n = 34) | NS |
| DFS at 10 years | 89% (n = 108) | 88% (n = 78) | 91% (n = 31) |
Abbreviations: DCIS pure DCIS, miCa microinvasive carcinoma, DFS disease-free survival, NS not significant, (*) characterizing the difference between DCIS and miCa