Table 3.

Analysis of significantly hypermethylated differentially methylated probes (DMPs)

GO ID	Description	P Value	Genes
Biological process
GO:0048002	antigen processing and presentation of peptide antigen	4.27E-04	HLA-A, HLA-C, HLA-DRA
GO:0019882	antigen processing and presentation	3.70E-03	HLA-A, HLA-C, HLA-DRA
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.86E-02	HLA-A, HLA-C
Cellular component
GO:0042611	MHC protein complex	1.71E-03	HLA-A, HLA-C, HLA-DRA
GO:0042612	MHC class I protein complex	3.02E-02	HLA-A, HLA-C
GO:0005626	insoluble fraction	5.95E-02	ELOVL2, HLA-C, CYP2E1, CAPN2
GO:0044459	plasma membrane part	7.76E-02	HLA-A, HLA-C, CACNA1E, TM4SF1, AFAP1, HLA-DRA
GO:0005886	plasma membrane	8.86E-02	NRP1, HLA-A, HLA-C, CACNA1E, TM4SF1, CAPN2, AFAP1, HLA-DRA
GO:0031224	intrinsic to membrane	8.97E-02	ZPLD1, NRP1, ELOVL2, HLA-A, HLA-C, CACNA1E, TM4SF1, LOC153328, CYP2E1, HLA-DRA
Molecular function
GO:0032393	MHC class I receptor activity	2.07E-02	HLA-A, HLA-C
GO:0032395	MHC class II receptor activity	2.31E-02	HLA-C, HLA-DRA