Table 2.

Comparison of frozen section and final pathology reveals that most discrepant cases were the underestimation of AIS and MIA

Frozen section diagnosis	Final pathology								Total (n=803)
	AAH (n=32)		AIS (n=126)		MIA (n=273)		IA (n=372)
	Number	%	Number	%	Number	%	Number	%
AAH	32	100	27	21.4	7	2.6	0	0	66
AIS	0	0	93	73.8	57	20.9	6	1.6	156
MIA	0	0	1	0.8	206	75.5	17	4.6	224
IA	0	0	0	0	2	0.7	347	93.3	349
Benign lesion	0	0	5	4.0	1	0.4	2	0.5	8

Note: Liu S, Wang R, Zhang Y, et al. Precise diagnosis of intraoperative frozen section is an effective method to guide resection strategy for peripheral small-sized lung adenocarcinoma. J Clin Oncol. 34:307–313. Reprinted with permission © 2016 American Society of Clinical Oncology. All rights reserved.40

Abbreviations: AAH, atypical adenomatous hyperplasia; AIS, adenocarcinoma in situ; IA, invasive adenocarcinoma; MIA, minimally invasive adenocarcinoma.