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. 2018 Jan 31;11:255–263. doi: 10.2147/JPR.S140369

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© 2018 An et al. This work is published and licensed by Dove Medical Press Limited

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VAS and von Frey of patients in different periods.

Notes: (A and B) Evolution of pain intensity: the pain intensity assessed by the VAS before ozone therapy (pretreatment), after ozone therapy (post-treatment) and at 6-month follow-up (follow-up). Values are presented as mean ± SD. (A) There was a significant decrease in pain intensity (*P < 0.05) after the ozone therapy, and this was maintained even up to 6 months of the follow-up (**P < 0.05). (B) There was a significant decrease in pain intensity after the ozone therapy in both groups (^−,+P < 0.05), and this was even maintained for up to 6 months of the follow-up (⁻⁻,⁺⁺P < 0.05). However there were no differences between these two groups at any time point (P > 0.05). (C and D) Evolution of tactile detections: the tactile intensity assessed by the von Frey before ozone therapy (pretreatment), after ozone therapy (post-treatment). Values are presented as mean ± SD. (C) There was no difference in von Frey (P > 0.05) before and after the ozone therapy. (D) No difference was found in von Frey of group A before and after the treatment (P > 0.05), while there was a significant decrease in von Frey (^&P < 0.05) of group B after the ozone therapy. Moreover the pretreatment von Frey of group B was significantly higher compared to group A (^#P < 0.05), but no difference was observed between these two groups after the therapy (P > 0.05).

Abbreviation: VAS, visual analog scale.