Table 1.
Model | Equation1 | |
---|---|---|
Linear2 | (a * AGE) + b | |
Power2 | b *AGEa | |
Exponential2 | b * ea * AGE | |
Linear-Log2 | b + [a *ln(AGE)] | |
Sigmoid Emax3 |
|
the covariate AGE was specified using either postnatal age (days) or postmenstrual age (weeks)
a and b denote estimable parameters associated with the linear, power, exponential, and linear-log models
AAGmax (maximum plasma AAG concentration [mg/dL]), TM50(age at 50% AAGmax [days or weeks]), and P (Hill coefficient) denote estimable parameters associated with the sigmoid Emax model