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Spinally evoked motor responses in intact animals before (Pre CTZ), 10–30mins and 60–90mins after (Post CTZ) in the (a) lateral gastrocnemius (LG) and (b) tibialis anterior (TA) muscles. Data are presented as percentage mean ± SD of Pre CTZ values. Systemic administration of h-CTZ caused significant reductions in evoked responses in the LG (a; ***p=0.0003) and TA (b; ***p=0.0009) at 10–30mins Post CTZ and in the TA (b; *p=0.04) at 60–90mins Post CTZ.
