Table 1.
Statistics for neuropsychological tests and behavioral questionnaires – Comparison between bvFTD and healthy control subjects.
| bvFTD patients |
Healthy controls |
|||||||
|---|---|---|---|---|---|---|---|---|
| Median | Mean (SD) | Median | Mean (SD) | U | Z | p | r | |
| Neuropsychological tests | ||||||||
| Stroop task | 96.7 | 86.18 (22.69) | 100 | 98.87 (2.91) | 552 | -3.378 | 0.001∗ | -0.35 |
| Trail Making Test (TMT) | 2.79 | 2.92 (1.16) | 2.11 | 2.13 (0.45) | 609.5 | -3.391 | 0.001∗ | -0.35 |
| Hamasch Five-Point Test (H5PT) | 77 | 67.31 (27.53) | 95 | 93.65 (6.02) | 414.5 | -5.007 | <0.001∗ | -0.50 |
| Phonemic fluency | 7 | 7.41 (4.90) | 18 | 17.83 (4.55) | 192.5 | -7.776 | <0.001∗ | -0.72 |
| Semantic fluency | 11 | 12.46 (6.71) | 26.5 | 26.48 (4.72) | 171 | -8.079 | <0.001∗ | -0.69 |
| Reading the Mind in the Eyes Test (RMET) | 11 | 10.83 (3.79) | 16 | 16.71 (2.56) | 214.5 | -6.272 | <0.001∗ | -0.64 |
| Behavioral questionnaires | ||||||||
| Apathy Evaluation Scale (AES), self-report | 21 | 20.26 (9.64) | 9 | 9.79 (4.91) | 91.0 | -3.696 | <0.001∗ | -0.55 |
| Apathy Evaluation Scale, informant-report | 36 | 34.95 (10.00) | 9 | 11.73 (6.63) | 42.5 | -5.504 | <0.001∗ | -0.61 |
| Bayer Activities of Daily Living Scale (BADL), self-report | 1.88 | 3.03 (2.66) | 1.38 | 1.46 (0.46) | 158.0 | -2.933 | 0.003∗ | -0.42 |
| Bayer Activities of Daily Living Scale, informant-report | 5.68 | 5.68 (2.79) | 1.26 | 1.40 (0.50) | 40.5 | -5.395 | <0.001∗ | -0.59 |
| Frontal Systems Behavioral Scale (FrSBe), frequency, self-report | 45 | 51.04 (20.81) | 36 | 37.00 (8.47) | 153.5 | -2.777 | 0.005∗ | -0.40 |
| Frontal Systems Behavioral Scale, frequency, informant-report | 72 | 73.10 (17.97) | 31 | 34.80 (9.35) | 27.0 | -5.650 | <0.001∗ | -0.64 |
| Frontal Systems Behavioral Scale, distress, self-report | 36 | 39.18 (14.09) | 28 | 31.82 (10.14) | 158 | -1.989 | 0.047 | -0.30 |
| Frontal Systems Behavioral Scale, distress, informant-report | 58.5 | 60.47 (17.15) | 24 | 27.46 (6.00) | 16.5 | -5.365 | <0.001∗ | -0.64 |
Significant with Bonferroni adjusted alpha level of ∗p < 0.008 for neuropsychological tests, p < 0.006 for behavioral questionnaires; Abbreviations: r, effect size; SD, standard deviation; U, Mann–Whitney U; Z, test statistic of Mann–Whitney U.