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. 2018 Jan 30;9:81. doi: 10.3389/fimmu.2018.00081

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Copyright © 2018 Li, Xiao, Tang, Zhong, Huang, Xu, Xu, Dai and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Adipocyte fatty acid-binding protein (A-FABP) inhibition with BMS309403 restores the expression of PGC-1α in macrophages. Thp-1 cells were pretreated with 50 µM BMS309403 for 2 h followed by 500 µM palmitate (PA) treatment. (A) Quantitative analysis of A-FABP mRNA level determined by real-time polymerase chain reaction. (B) Western blot of PGC-1α (top panel) and its semiquantitative analysis (lower panel). **P < 0.01 versus control, ^#P < 0.05 Vehicle versus BMS309403 (n = 4 for each group).