Fig. 6.

Prognostic implications of late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) in patients with severe aortic stenosis and aortic regurgitation after aortic valve replacement surgery. Linear regression graphs illustrate the inverse relationship between the degree of left ventricular ejection fraction improvement and the amount of myocardial fibrosis by histopathology (A) and by LGE CMR (B). The Kaplan–Meier graphs demonstrate significantly worse survival after aortic valve replacement in patients with larger myocardial fibrosis assessed by histopathology (C) or LGE (D). Reproduced with permission from Azevedo et al. [33] ce-MRI contrast-enhanced magnetic resonance imaging, EF ejection fraction, MF myocardial fibrosis