Table 1.
Patients demographics
| Post-MI | Idiopathic | NIDCM | PLN/LMNA | p value | |
|---|---|---|---|---|---|
| Total Pts | 16 | 16 | 16 | 16 | |
| Age (years) | 55 (53–63) | 45 (40–61) | 54 (38–60) | 52 (40–57) | 0.042 |
| Pediatric (%/n) | 0% (0) | 0% (0) | 6.2% (1) | 6.2% (1) | 0.559 |
| Sex (%male/n) | 93.8% (15) | 50% (8) | 56.2% (9) | 50% (8) | 0.028 |
| Length (m) | 1.78 ± 0.1 | 1.76 ± 0.1 | 1.76 ± 0.1 | 1.71 ± 0.1 | 0.296 |
| Weight (kg) | 88 ± 15 | 82 ± 15 | 83 ± 21 | 71 ± 14 | 0.029 |
| BMI | 28 ± 3 | 27 ± 3 | 27 ± 5 | 24 ± 3 | 0.026 |
| Any anti-arrhythmic drugs | 93.8% (15) | 56.2% (9) | 68.8% (11) | 62.5% (10) | 0.102 |
| - Class I | 0% (0) | 12.5% (2) | 0% (0) | 0% (0) | 0.103 |
| - Beta blockers | 81.2% (13) | 37.5% (6) | 43.8% (7) | 56.2% (9) | 0.064 |
| - Class III | 25.0% (4) | 12.5% (2) | 43.8% (7) | 25.0% (4) | 0.252 |
| - Class IV | 6.2% (1) | 6.2% (1) | 6.2% (1) | 0.0% (0) | 0.789 |
| - Digoxin | 6.2% (1) | 0% (0) | 6.2% (1) | 37.5% (6) | 0.006 |
| LVEF | < 0.001 | ||||
| - Normal (> 55%) | 6.2% (1) | 93.8% (15) | 18.8% (3) | 31.2% (5) | |
| - Mild dysfunction (45–54%) | 31.2% (5) | 6.2% (1) | 37.5% (6) | 6.2% (1) | |
| - Moderate dysfunction (30–44%) | 18.8% (3) | 0% (0) | 18.8% (3) | 12.5% (2) | |
| - Severe dysfunction (< 30%) | 43.8% (7) | 0% (0) | 25.0% (4) | 50.0% (8) | |
| Monomorphic PVCs | 13% (2) | 100% (16) | 44% (7) | 6% (1) | < 0.001 |
| Polymorphic PVCs | 88% (14) | 0% (0) | 56% (9) | 94% (15) | < 0.001 |
| Ventricle of origin | < 0.001 | ||||
| - Left | 100% (16) | 25.0% (4) | 50.0% (8) | n.a.* | |
| - Right | 0% (0) | 75.0% (12) | 37.5% (6) | n.a.* | |
| - Both | 0% (0) | 0% (0) | 12.5% (2) | n.a.* | |
| Arrhythmia focus | n.a.* | < 0.001 | |||
| - RVOT | 0% (0) | 75.0% (12) | 31.2% (5) | n.a.* | |
| - LVOT | 0% (0) | 25% (4) | 25% (4) | n.a.* | |
| - Other | 100% (16) | 0% (0) | 43.8% (7) | n.a.* | |
| PVC characteristics (of dominant morphology) | |||||
| - LBBB + superior axis | n.d.# | n.d.# | n.d.# | 18.8% (3) | |
| - RBBB + superior axis | n.d.# | n.d.# | n.d.# | 18.8% (3) | |
| - LBBB + inferior axis | n.d.# | n.d.# | n.d.# | 25% (4) | |
| - RBBB + inferior axis | n.d.# | n.d.# | n.d.# | 37.5% (6) | |
Descriptive statistics are presented as mean ± SD for continuous variables, if normally distributed, or otherwise by median with (25th and 75th percentile). (*Not applicable: no ablation was done in this group of patients; therefore, the exact origin of the PVCs was not determined by electroanatomical mapping; PVC characteristics, indicative of PVC foci, are presented as a surrogate. #Not displayed: in case electroanatomical mapping is available, no PVC characteristics are displayed.)
BMI body mass index, LBBB left bundle branch block, LVEF left ventricular ejection fraction, LVOT left ventricular outflow tract, RBBB right bundle branch block, RVOT right ventricular outflow tract