. 2018 Jan 31;9:76. doi: 10.3389/fimmu.2018.00076

Table 1.

Patient characteristics.

	FPF	HPSPF	URel	p-Value
Age (years)	63.4 ± 3.2	42.0 ± 2.9	43.3 ± 9.3	<0.001^a
				0.060^b
				0.86^c
Gender (M/F)	1/4	2/10	3/1
FVC (% predicted)	89.0 ± 10.5	67.8 ± 5.7	120.5 ± 3.6	0.073^a
				0.037^b
				<0.001^c
TLC (% predicted)	87.0 ± 7.6	73.6 ± 6.1	115.3 ± 5.0	0.23^a
				0.022^b
				0.002^c
DLCOa (% predicted)	55.4 ± 11.8	43.2 ± 4.6	92.5 ± 8.2	0.25^a
				0.045^b
				<0.001^c
HRCT scan	Fibrosis	Fibrosis	No fibrosis

FPF, familial pulmonary fibrosis; HPSPF, Hermansky–Pudlak syndrome pulmonary fibrosis; URel, unaffected relative; M, male; F, female; FVC, forced vital capacity; TLC, total lung capacity; DLCOa, diffusion capacity (adjusted); HRCT, high-resolution computed tomography.

^aFPF vs HPSPF.

^bFPF vs URel.

^cHPSPF vs URel.