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Representative dose delivery patterns of (A) low-LET photons and (B) charged particles. (B) Charged particles demonstrate a low-LET plateau region before the high-LET Bragg peak. (C) Exposures with varying initial energies (gray lines) can be used to create a SOBP (red line) and cover the entire volume of targeted tissue with approximately the same dose of radiation. Abbreviations: LET, linear energy transfer; SOBP, spread-out Bragg peak.
