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. 2018 Jan 31;9:49. doi: 10.3389/fphar.2018.00049

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Copyright © 2018 Zeng, Lin, Zheng, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Celastrol treatment decreases the frequency of Th17 cell expansion. Proportion of Th17 cells in CD4⁺T cells was determined by flow cytometry. The data were expressed as mean ± SD (n = 6). ^∗∗P < 0.01 compared with Sham group; ^##P < 0.01 compared with DIO+OVA+DMSO group.