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. 2018 Jan 31;9:49. doi: 10.3389/fphar.2018.00049

Table 1.

Celastrol reduces the airway resistence (Rn) of obese asthmatic mice.

Group n Rn (cmH2O/ml/s)
Sham 6 0.3503 ± 0.0032
OVA+DMSO 6 0.5463 ± 0.1226∗∗
DIO +DMSO 6 0.4483 ± 0.0010
DIO+OVA+DMSO 6 0.6550 ± 0.0972∗∗
DIO+OVA+Celastrol 6 0.4127 ± 0.0443##

Airway resistence (Rn) was determined by Mouse ventilator and forced oscillation technique within 24 h after last challenge. The data were expressed as mean ± SD (n = 6). P < 0.05; ∗∗P < 0.01 compared with Sham group; ##P < 0.01 compared with DIO+OVA+DMSO group.