Table 1.
Odds ratios for microalbuminuria estimated using logistic regression.
| Protein | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 |
|---|---|---|---|---|---|
| sTNFR1 | 5.47 (3.83–8.15)¶ | 4.80 (3.36–7.16)¶ | 4.58 (3.17–6.90)¶ | 4.78 (3.29–7.27)¶ | 4.03 (2.74–6.20)¶ |
| sTNFR2 | 4.85 (3.29–7.36)¶ | 3.87 (2.62–5.91)¶ | 3.41 (2.30–5.20)¶ | 3.44 (2.32–5.26)¶ | 2.83 (1.87–4.42)¶ |
| sIL2Rα | 2.79 (2.14–3.70)¶ | 2.59 (1.98–3.45)¶ | 2.55 (1.92–3.44)¶ | 2.60 (1.96–3.51)¶ | 2.61 (1.92–3.61)¶ |
| MMP2 | 2.30 (1.67–3.24)¶ | 1.85 (1.34–2.63)‡ | 1.51 (1.08–2.17)* | 1.52 (1.09–2.19)* | 1.56 (1.08–2.31)* |
| sgp130 | 1.87 (1.37–2.59)‡ | 1.83 (1.32–2.57)‡ | 1.77 (1.26–2.54)† | 1.78 (1.26–2.56)† | 1.90 (1.29–2.83)† |
| sVCAM1 | 1.69 (1.27–2.27)‡ | 1.61 (1.20–2.19)† | 1.68 (1.23–2.33)† | 1.68 (1.23–2.33)† | 1.73 (1.23–2.45)† |
| CRP | 1.52 (1.17–2.01)† | 1.48 (1.12–1.98)† | 1.57 (1.17–2.14)† | 1.56 (1.16–2.13)† | 1.33 (0.97–1.84) |
| sIL6R | 1.72 (1.21–2.54)† | 1.70 (1.17–2.55)† | 1.68 (1.13–2.59)* | 1.68 (1.13–2.58)* | 1.58 (1.06–2.46)* |
| SAA | 1.37 (1.07–1.77)* | 1.24 (0.96–1.61) | 1.39 (1.05–1.85)* | 1.37 (1.04–1.83)* | 1.17 (0.87–1.59) |
| sICAM1 | 1.34 (1.06–1.70)* | 1.26 (0.98–1.61) | 1.25 (0.96–1.62) | 1.23 (0.95–1.60) | 1.18 (0.90–1.56) |
| MMP1 | 1.22 (0.96–1.56) | 1.11 (0.86–1.44) | 1.22 (0.93–1.59) | 1.22 (0.93–1.59) | 1.10 (0.83–1.47) |
| MMP9 | 0.99 (0.79–1.27) | 1.03 (0.81–1.35) | 1.05 (0.8–1.39) | 1.04 (0.80–1.39) | 1.06 (0.8–1.46) |
Values presented are odds ratio (95% CI). Model 1 = protein concentration only, Model 2 = protein concentration + age, Model 3 = Model 2 + duration of T1D, Model 4 = Model 3 + gender, and Model 5 = Model 4 + hypertension and dyslipidemia.
*P < 0.05, †P < 0.01, ‡P < 0.001, and ¶P < 1 × 10−5.