Table 1.
Clinical and biochemical characteristics of the study subjects.
| Variables | ALL | H. pylori negative | H. pylori positive | P |
|---|---|---|---|---|
| N | 28,171 | 17,323 | 10,848 | |
| Sex (M/F) | 14,389/13,782 | 8,537/8,786 | 5,852/4,996 | <0.001 |
| Age (years) | 48.3 ± 15.0 | 48.2 ± 15.1 | 48.3 ± 14.9 | 0.581 |
| BMI (kg/m2) | 23.7 ± 3.2 | 23.5 ± 3.2 | 23.9 ± 3.3 | <0.001 |
| SBP (mmHg) | 126.9 ± 19.6 | 126.4 ± 19.4 | 127.6 ± 20.0 | <0.001 |
| DBP (mmHg) | 73.8 ± 11.2 | 73.4 ± 11.1 | 74.4 ± 11.5 | <0.001 |
| FPG (mM) | 5.3 ± 1.0 | 5.4 ± 1.0 | 5.3 ± 1.0 | 0.788 |
| HbA1c (%) | 5.7 ± 1.1 | 5.7 ± 1.1 | 5.7 ± 1.0 | 0.304 |
| TG (mM) | 1.5 ± 1.2 | 1.4 ± 1.2 | 1.5 ± 1.2 | 0.032 |
| TC (mM) | 4.8 ± 0.9 | 4.8 ± 0.9 | 4.8 ± 0.9 | 0.052 |
| LDL-C (mM) | 2.9 ± 0.8 | 2.9 ± 0.8 | 3.0 ± 0.8 | <0.001 |
| HDL-C (mM) | 1.5 ± 0.4 | 1.5 ± 0.4 | 1.4 ± 0.4 | <0.001 |
| UA (μM) | 320.7 ± 86.8 | 318.8 ± 86.5 | 323.8 ± 87.2 | <0.001 |
| Scr (μM) | 70.6 ± 20.9 | 70.1 ± 20.5 | 71.3 ± 21.5 | <0.001 |
| ALT (IU/L) | 17 (12–24) | 16 (12–23) | 17 (12–24) | <0.001 |
| AST (IU/L) | 19 (16–23) | 19 (16–22) | 19 (16–23) | 0.113 |
Subjects were divided into two groups according to H. pylori infection status. Continuous variables were presented as means ± SD or median (interquartile range) Differences between two groups were tested by student’s oxt-test for continuous variables and x2 test for categorical variables. BMI, body mass index; SBP, systolic and diastolic blood pressure; DBP, diastolic blood pressure; TG, triglycerides, TC, total cholesterol, LDL-C, low-density lipoprotein cholesterol, HDL-C, high-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Scr, serum creatinine; UA, uric acid.