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. 2018 Jan 31;12:19. doi: 10.3389/fncel.2018.00019

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Copyright © 2018 Anzabi, Ardalan, Iversen, Rafati, Hansen and Østergaard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Illustration of the main steps for the procedures: SAH induction by the endovascular circle of Willis perforation (CWp). (A) Left external carotid artery (ECA), common carotid artery (CCA) and internal carotid artery (ICA) were exposed. (B) ICA and CCA were blocked temporarily with microclips while the ECA was ligated permanently as far cranially as possible. A prearranged ligation was made around the ECA right after the bifurcation of the CCA in order to hold the filament. (C) A small incision was cut into ECA for the filament insertion. (D) The filament was inserted into ECA, and the insertion part was closed by the prearranged ligation. (E) Microclips were removed from CCA and MCA, and the filament advanced toward the skull base via ICA, until a sharp rise in ICP was observed. (F) The filament was withdrawn and the ECA was closed by tightening of the prearranged ligation.