Figure 5.
Phlebotomy influences the histopathology of crocidolite‐induced malignant mesothelioma (MM) in rats. A, Difference in the fraction of MM subtypes. The number of rats with the biphasic subtype and those without a tumor were increased among those that underwent phlebotomy four times per month (weekly; Phleb‐4) or twice per month (biweekly; Phleb‐2). B, Summary table of the fraction of MM subtypes. Phlebotomy modestly reduced the sarcomatoid subtype, comparing the non‐therapeutic (NT) vs Phleb groups for non‐sarcomatoid vs sarcomatoid groups. Analysis by the χ2‐test