Table 3.

Analyses of the relationship between ulinastatin treatment and outcomes

Outcome	OR	95% CI of OR	P‐value
Primary outcome: 28‐day all‐cause mortalitya
Crude	1.62	0.82–3.19	0.162
Adjusted for APACHE II score	1.59	0.79–3.21	0.195
Multivariable adjustedb	1.22	0.54–2.79	0.632
Secondary outcomes
ICU‐free daysc
Crude	0.31	0.19–0.52	<0.001
Multivariable adjustedb	0.44	0.25–0.75	0.003
Ventilator‐free daysc
Crude	0.42	0.25–0.69	<0.001
Multivariable adjustedb	0.49	0.28–0.84	0.010
Vasopressor‐free daysc
Crude	0.50	0.31–0.82	0.006
Multivariable adjustedb	0.66	0.38–1.15	0.143

^aLogistic regression.

^bAdjusted for APACHE II score, sepsis, corticosteroid use, vasopressor use, renal replacement therapy, and venoarterial extracorporeal membranous oxygenation.

^cOrdinal logistic regression.

APACHE II, acute physiology and chronic health evaluation II; CI, confidence interval; ICU, intensive care unit; OR, odds ratio.