Table 2.
Clock-controlled transport genes in the kidney
Gene | Function | RNA Source | Reference |
---|---|---|---|
Slc9a3 (NHE3) | Sodium/hydrogen exchange | Whole kidney | 66 |
Gilz | Leucine zipper protein/regulation of sodium transport | DCT, CNT, CCD. Whole kidney | 61 |
Usp2 | Ubiquitin specific protease/regulation of sodium transport | DCT, CNT, CCD. Whole kidney | 61 |
V1aR | Vasopressin receptor/regulation of water balance | DCT, CNT, CCD. Whole kidney | 61 |
V2R | Vasopressin receptor/regulation of water balance | DCT, CNT, CCD. Whole kidney | 61 |
Slc6a6 | Taurine transporter | CCD | 61 |
Slc6a9 | Glycine transporter | DCT/CNT | 61 |
Aqp2 | Water channel | CCD | 61 |
Aqp4 | Water channel | CCD | 61 |
Scnn1a (αENaC) | Alpha subunit of epithelial sodium channel | Cortex, outer medulla and inner medulla | 65 |
DCT, distal convoluted tubule; CNT, connecting tubule; CCD, cortical collecting duct.