Table 3.
Summary of studies of CMRI in transplant recipients
Author | Population | Technique | Results/conclusions |
---|---|---|---|
Malatesta-Muncher et al. [96] | Pediatric: ESRD (10 dialysis/10 transplant) versus 24 healthy controls | CMRI and CMRS | CMRI and MRS detected subclinical cardiac dysfunction, decreased energy metabolism and myocardial microcomposition in ESRD patients, despite normal EF |
Schaefer et al. [97] | Pediatric: 15 children (2 CKD, 6 PD, 7 HD, 18 transplants) | CMRI (before and after transplant | All CMRI parameters (EF, end diastolic LV volume index, end systolic LV volume index and LVMI) improved after transplant |
Parnham et al. [98] | Adult: 12 CKD, 11 dialysis, 10 transplant, 10 HTN controls, 10 healthy controls | BOLD CMRI | CKD, dialysis and transplant had impaired myocardial response to stress in comparison to HTN and normal controls |
Arnold et al. [99] | Pediatric: 25 CKD (14 post-transplant) | CMRI versus standard echocardiography | Echo underestimates LVM compared to CMRI |
CMR-LVMI but not echo-LVMI predicted future GFR decline | |||
Gimpel et al. [100] | Pediatric: 20 CKD/transplant versus 12 healthy controls | CMRI tissue phase mapping | Reduced regional LV wall velocities in CKD and transplant, with normal LVH |
ESRD, end-stage renal disease; HD, hemodialysis; HTN, hypertension; LVMI, left ventricular mass index; MRS, magnetic resonance spectroscopy; PD, peritoneal dialysis.