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. 2017 Dec 18;7(2):e1378844. doi: 10.1080/2162402X.2017.1378844

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 3. — Tertiary lymphoid structure parameters and 3-year risk of colorectal cancer recurrence. Patients with low TLS counts (A), high proportions of E-TLS (B), and low proportions of PFL-TLS (C) showed a tendency towards numerically higher risks of recurrence. Patients with low SFL-TLS proportion (D) experienced a significantly higher risk of recurrence. Absolute risk estimates corresponding to these curves are reported in Table 2. Recurrence risks were estimated with competing risk analysis, treating death-from-any-cause as the competing event of interest. In the risk table, numbers in brackets represent the number of recurrences in the respective time interval. Abbreviations: Q1 – Cut-off at the 25^th percentile of the variables' distribution (i.e. quartile 1), Q3 – Cut-off at the 75^th percentile of the variable's distribution (i.e. quartile 3).