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. Author manuscript; available in PMC: 2018 Feb 5.
Published in final edited form as: J Urol. 2014 Jun 10;192(4):1238–1248. doi: 10.1016/j.juro.2014.05.115

Figure 4.

Figure 4

Effect of BCG internalization on real time ROS/RNS profiling: T24 and 253J cells were exposed to BCG for 6h. Post BCG exposure, H2O2 levels were measured using CBA and AR, O2− levels were measured using HE and NO levels were measured using DAF-2DA. Treatment groups included Untreated, Cytochalasin-B treated, BCG treated and BCG with cytochalasin-B. H2O2, O2− and NO levels significantly decreased in the BCG with cytochalasin-b treatment group in both cell lines, relative to BCG alone. (p < 0.05 for H2O2, p < 0.01 for O2− and p < 0.05 for NO). The difference in Cytochalasin-b control group and cytochalasin-b plus BCG group was statistically non-significant (p = 0.4).