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. Author manuscript; available in PMC: 2018 Feb 5.
Published in final edited form as: ACS Infect Dis. 2016 Nov 3;3(1):62–71. doi: 10.1021/acsinfecdis.6b00133

Table 1.

MICa of ECC145 and ECC188 against Common Nosocomial Bacterial Pathogens

MIC for ECC145 (µg/mL) MIC for ECC188 (µg/mL)
organism (n) 50% 90% range 50% 90% range
Escherichia coli (10) >512 >512 >512 >512 >512 256–>512
Staphylococcus aureus (9) 256 256 128–>512 256 512 128–>512
Klebsiella pneumoniae (10) >512 >512 >512 >512 >512 >512
Acinetobacter baumannii (44) 8 8 2–16 4 8 1–8
Pseudomonas aeruginosa (10) 512 512 128–>512 512 512 256–>512
a

MIC in cation-adjusted Mueller–Hinton broth, 22 h.